Neutropenia Definition

Neutropenia definition can be summarized as a condition where the neutrophils level is peculiarly low in the blood. They are WBCs (white blood cells) formed within the bone marrow to consume bacteria. Granulocytopenia or agranulocytosis is word used at times to give the Neutropenia definition as neutrophils sums up of about sixty percent of white blood cells and have pellets within the walls of the cell. Neutropenia definition mentions that it is a severe disorder since it turns the body defenseless to fungal and bacterial infections. 

Description of the Neutropenia Disease:

The standard intensity of neutrophils in blood differs slightly by race and age. Children have lesser counts as compared to the adults, and Afro-Americans have lesser counts as compared to the Asian or Caucasians. The normal adult intensity is 1500 cells per mm3. The counts of Neutrophil are stated as follows:

  • If the count is more than 1000 then there is normal defense against any infection.
  • If the count is between 500-1000 then there is an increased threat of infection.
  • If the count is 200-500 then there is great danger of rigorous infection.
  • If the count is under 200. There are chances of irresistible infection; which needs hospital healing along with antibiotics.

Symptoms and causes and that the Neutropenia Disease explains: There are usually three reasons when there is Neutropenia:

1.   Lesser production of White blood cells: Lesser production of WBCs is the most general reason of Neutropenia Disease. This might occur from:

  • medicines that influence the bone marrow, for instance, Chloromycetin (chloramphenicol), cancer drugs, medications for anticonvulsant, and drugs for phenothiazines, Prolixin, and Thorazine.
  • Congenital and hereditary disorders that influence human bone marrow, as well as cyclic neutropenia, familial neutropenia, and cancer of infantile agranulocytosis, together with certain kinds of radiation therapy of leukemia, contact with pesticides, deficiency of folic acid and vitamin B12.

2.   Damage of white blood cells. White blood cells are consumed at a faster speed by:

  • Infections such as acute bacterial caused in adults.
  • Newborns suffering with different infections.
  • A few disorders of autoimmune, including SLE (systemic lupus erythematosus), penicillin, Dilantin (phenytoin), and medications of sulfonamide (Gantanol , Bactrim, Benemid).

3. Margination and Sequestration of white blood cells: margination and sequestration are progressions in where neutrophils are detached from the common blood transmission and regiveout in the body. Such progressions might happen because of: Malaria or even syndrome of Hemodialysis felty’s. According to the detailed Neutropenia Disease the neutrophils stay behind in the tainted tissues with no returning back to the human blood flow.

Neutropenia Symptoms:

Neutropenia has no precise indications with the exception of the rigorousness of the human body’s present infection. In cases where neutropenia is severe, the human body is likely to increase disease such as periodontal, rectal and oral ulcers, pneumonia of bacteria, and fever. Recurring fever every 18-20 days puts forward cyclical neutropenia.

Prognosis according to the Neutropenia Disease:

The prognosis for chronic or mild neutropenia is exceptional. Healing from sensitive neutropenia relies on the sternness of the human body infection and the rapidity of the treatment.

Neutropenia Definition
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